Impact of Static Magnetic Field on the Antioxidant Defence System of Mice Fibroblasts

Abstract

Results of research assessing the biological impact of static magnetic felds are controversial. So far, they have not provided a clear answer to their infuence on cell functioning. Since the use of permanent magnets both in everyday life and in industry becomes more and more widespread, the investigations are continued in order to explain these controversies and to evaluate positive applications. Te goal of current work was to assess the impact of static magnetic feld of diferent intensities on redox homeostasis in cultures of fbroblasts. Te use of permanent magnets allowed avoiding the thermal efects which are present in electromagnets. During the research we used 6 chambers, designed exclusively by us, with diferent values of feld fux density (varying from 0.1 to 0.7 T). We have noted the decrease in the activity of superoxide dismutase (SOD) and glutathione peroxidase (GPx). Te static magnetic felds did not modify the energy state of fbroblasts— adenosine triphosphate (ATP) concentration was stable, as well as the generation of malondialdehyde (MDA)—which is a marker of oxidative stress. Results of research suggest that static magnetic felds generated by permanent magnets do not cause oxidative stress in investigated fbroblasts and that they may show slight antioxidizing activity.
5053608

Authors:
Marek Glinka,1 Stanisław Gawron,1 Aleksander Sieroń,2 Katarzyna Pawłowska-Góral,3 Grzegorz Cieślar,2 and Karolina Sieroń4
1 Research and Development Centre of Electrical Machines “Komel”, 188 Rozdzienskiego St., 40-203 Katowice, Poland
2 Department of Internal Medicine, Angiology and Physical Medicine in Bytom, School of Medicine with Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, 15 Batorego St., 41-902 Bytom, Poland
3 Department of Food and Nutrition in Sosnowiec, Medical University of Silesia in Katowice, 8 Jednosci St., 41-200 Sosnowiec, Poland
4 Department of Physical Medicine, Chair of Physiotherapy, School of Health Sciences, Medical University of Silesia, Medykow 12 St., 40-752 Katowice, Poland

BioMed Research International
Volume 2018 (2018), Article ID 5053608, 8 pages
https://doi.org/10.1155/2018/5053608

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Impact of Static Magnetic Field on the Antioxidant Defence System of Mice Fibroblasts

 

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